Well this was an interesting read. That weight savings is significant and should only improve the ride with such a large reduction in unsprung weight.
As far as OEM wheels, unless they are forged (think true M cars) BMW has historically made some of the softest and heaviest cast alloy wheels...constantly bending or cracking with runflats. Moving to a rotary forged or fully forged wheel won't increase the risk of structural wheel damage, if the load rating is similar or better than OEM spec.
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